How many days do you need in Prague? Four days is enough to see the main sights without rushing and still get out of the tourist centre. This 4-day Prague itinerary covers one area per day, so you walk between nearby stops instead of crossing the city.
Day 1 is the Old Town: the Powder Tower, Old Town Square and the Astronomical Clock, the Jewish Quarter, then up to Letná Park for the view over the bridges. Day 2 is Prague Castle and St. Vitus Cathedral, then downhill through Malá Strana and Kampa Island to Charles Bridge.
Day 3 is a slower café day in Vinohrady and Žižkov, ending with the sunset from Riegrovy Sady. Day 4 goes from Wenceslas Square to the Dancing House, along the Náplavka riverside and up to the Vyšehrad fortress.
Each day is 2 to 3 km of walking between stops, under 45 minutes of actual walking time, so there is plenty of time for museums, food and coffee.