How many days do you need in Rome? Four days is enough to see the main sights without rushing. This 4-day Rome itinerary covers one area per day, so you walk between nearby stops and never backtrack across the city.
Day 1 is ancient Rome: the Colosseum, the Roman Forum and the Palatine Hill, ending at Piazza Venezia. Day 2 is the historic centre: the Spanish Steps, the Trevi Fountain, the Pantheon and Piazza Navona.
Day 3 is the Vatican: the Vatican Museums and Sistine Chapel, St Peter's Basilica, then Castel Sant'Angelo. Day 4 is Trastevere, up to the Gianicolo Terrace and across to the Orange Garden on the Aventine Hill for sunset.